(4R)-4-tert-butyl-2-{2-[(4R)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]propan-2-yl}-4,5-dihydro-1,3-oxazole
(R,R)-(-)-2,2'-Isopropylidenebis(4-Tert-Butyl-2-Oxazoline)
CAS: 131833-97-1
Molecular Formula: C17H30N2O2
(4R)-4-tert-butyl-2-{2-[(4R)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]propan-2-yl}-4,5-dihydro-1,3-oxazole - Names and Identifiers
| Name | (R,R)-(-)-2,2'-Isopropylidenebis(4-Tert-Butyl-2-Oxazoline) |
| Synonyms | (R,R)-(-)-2,2'-ISOPROPYLIDENEBOXAZOLINE) (R,R)-(+)-2,2-Isopropylidenebis(4-Tert-Butyl-2-Oxazolin (R,R)-(+)-2,2-Isopropylidenebis(4-Tert-Butyl-2-Oxazoline) (R,R)-(-)-2,2'-Isopropylidenebis(4-Tert-Butyl-2-Oxazoline) (R,R)-(-)-2,2'-ISOPROPYLIDENEBIS(4-TERT-BUTYL-2-OXAZOLINE) (4R,4'R)-2,2'-(Propane-2,2-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole) (4R,4'R)-2,2'-propane-2,2-diylbis(4-tert-butyl-4,5-dihydro-1,3-oxazole) (4R,4'R)- 2,2'-(1-Methylethylidene)bis[4-(1,1-diMethylethyl)-4,5-dihydro-Oxazole (4R)-4-tert-butyl-2-{2-[(4R)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]propan-2-yl}-4,5-dihydro-1,3-oxazole (R,R)-(+)-2,2'-(Dimethylmethylene)bis(4-tert-butyl-2-oxazoline)(R,R)-(+)-2,2-Bis(4-tert-butyl-2-oxazolin-2-yl)propane |
| CAS | 131833-97-1 |
| InChI | InChI=1/C17H30N2O2/c1-15(2,3)11-9-20-13(18-11)17(7,8)14-19-12(10-21-14)16(4,5)6/h11-12H,9-10H2,1-8H3/t11-,12-/m0/s1 |
(4R)-4-tert-butyl-2-{2-[(4R)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]propan-2-yl}-4,5-dihydro-1,3-oxazole - Physico-chemical Properties
| Molecular Formula | C17H30N2O2 |
| Molar Mass | 294.43 |
| Density | 1.04±0.1 g/cm3(Predicted) |
| Melting Point | 88.0 to 92.0 °C |
| Boling Point | 350.4±25.0 °C(Predicted) |
| Flash Point | 134.912°C |
| Solubility | soluble in Chloroform |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Almost white |
| pKa | 5.69±0.70(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.516 |
| MDL | MFCD07368371 |
(4R)-4-tert-butyl-2-{2-[(4R)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]propan-2-yl}-4,5-dihydro-1,3-oxazole - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| HS Code | 29349990 |
(4R)-4-tert-butyl-2-{2-[(4R)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]propan-2-yl}-4,5-dihydro-1,3-oxazole - Introduction
(R,R)-( )-2,2 '-isopropylidene bis (4-tertbutyl-2-oxazoline) is a chiral molecule with the following properties:
Appearance: colorless crystal
Molecular formula: C23H34N2O2
Molecular weight: 382.53g/mol
It is a very important chiral ligand and is widely used in catalytic asymmetric synthesis reactions. In organic synthesis, it can form chiral complexes with transition metals, which can be used to catalyze asymmetric oxidation, reduction, olefin cyclization and other reactions, and can produce high selectivity and high stereochemical reaction products.
In the preparation method, (R,R)-( )-2,2 '-isopropylidene bis (4-tert-butyl -2-oxazoline) can be synthesized through a two-step reaction. First, an isopropyl functional group is introduced at the head by an isopropylation reaction. The tert-butyl substituent is then introduced by tert-butylation. Finally, the target product is obtained by reduction. (Note that this is only a brief description of the synthesis steps, the specific reaction details and conditions may be different, so it is recommended to refer to professional literature guidance during synthesis)
This compound is relatively safe under normal circumstances, but the following matters still need to be paid attention:
-It is an organic compound with a certain degree of flammability. Contact with open flames or high temperature substances should be avoided.
-Try to avoid inhaling its dust or solution, because it may cause irritation to the respiratory tract and eyes.
-Wear appropriate personal protective equipment, such as goggles, lab coats and gloves.
-When using or storing, it should be stored in a closed container, away from heat and fire sources.
In summary,(R,R)-( )-2,2 '-isopropylidene bis (4-tert-butyl-2-oxazoline) is an important chiral ligand. It has a wide range of applications in asymmetric synthesis, but it should be used safely during operation.
Appearance: colorless crystal
Molecular formula: C23H34N2O2
Molecular weight: 382.53g/mol
It is a very important chiral ligand and is widely used in catalytic asymmetric synthesis reactions. In organic synthesis, it can form chiral complexes with transition metals, which can be used to catalyze asymmetric oxidation, reduction, olefin cyclization and other reactions, and can produce high selectivity and high stereochemical reaction products.
In the preparation method, (R,R)-( )-2,2 '-isopropylidene bis (4-tert-butyl -2-oxazoline) can be synthesized through a two-step reaction. First, an isopropyl functional group is introduced at the head by an isopropylation reaction. The tert-butyl substituent is then introduced by tert-butylation. Finally, the target product is obtained by reduction. (Note that this is only a brief description of the synthesis steps, the specific reaction details and conditions may be different, so it is recommended to refer to professional literature guidance during synthesis)
This compound is relatively safe under normal circumstances, but the following matters still need to be paid attention:
-It is an organic compound with a certain degree of flammability. Contact with open flames or high temperature substances should be avoided.
-Try to avoid inhaling its dust or solution, because it may cause irritation to the respiratory tract and eyes.
-Wear appropriate personal protective equipment, such as goggles, lab coats and gloves.
-When using or storing, it should be stored in a closed container, away from heat and fire sources.
In summary,(R,R)-( )-2,2 '-isopropylidene bis (4-tert-butyl-2-oxazoline) is an important chiral ligand. It has a wide range of applications in asymmetric synthesis, but it should be used safely during operation.
Last Update：2024-04-10 22:29:15
![(4R)-4-tert-butyl-2-{2-[(4R)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]propan-2-yl}-4,5-dihydro-1,3-oxazole](http://res.chembk.com/assets/str/2d/1/13/131833-97-1.png)
Supplier List
Spot supply
Product Name: (R,R)-(+)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline) Visit Supplier Webpage Request for quotationCAS: 131833-97-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: (R,R)-(+)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline) Visit Supplier Webpage Request for quotationCAS: 131833-97-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History